GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper-binding tripeptide that has attracted significant research interest due to its broad biological activity profile. Initially isolated from human plasma, it has been characterised as a potent modulator of tissue remodelling processes.
Preclinical research has investigated its role in wound contraction, collagen and glycosaminoglycan synthesis, anti-inflammatory cytokine modulation, and matrix metalloproteinase regulation. Studies have also explored its capacity to stimulate nerve regeneration, promote antioxidant defence mechanisms, and downregulate genes associated with cancer progression in cell culture models.
GHK-Cu is widely used as a research tool in dermatological, oncological, and regenerative medicine studies examining extracellular matrix remodelling. Research has also characterised its interaction with copper transport proteins and its role in maintaining tissue copper homeostasis. It is of particular interest in studies examining epigenetic regulation and gene expression modulation via its effects on histone acetylation.
Format: Lyophilised powder | Purity: ≥99% by HPLC | For Research Use Only
